Collapse Section Primary carnitine deficiency is a condition that prevents the body from using certain fats for energy, particularly during periods without food (fasting). Carnitine, a natural substance acquired mostly through the diet, is used by cells to process fats and produce energy. Clinically, carnitine deficiency manifests during childhood or early adult life as progressive proximal muscle weakness, myalgias, and rarely, myoglobinuria. Systemic carnitine deficiency is related to impaired hepatic biosynthesis and/or excessive renal excretion of carnitine. Plasma, liver, and muscle carnitine levels are reduced.
Carnitine deficiency is when not enough (less than 10%) of the nutrient carnitine is available to cells in the body. This can cause muscle weakness and heart or liver problems. You get carnitine through some of the foods you eat. It plays an important role in getting fatty acids into cells to use for energy. Carnitine is a nutrient that helps the body’s cells work normally. Secondary carnitine deficiency is when there isn’t enough carnitine in the blood. This can cause muscle weakness. It can also cause heart or .
Carnitine Deficiency is a metabolic condition wherein the body does not produced enough carnitine for metabolizing fats in the body. It is very essential to have normal levels of carnitine in the body because it helps in the body’s overall functioning. The onset of this metabolic condition is . Oct 10, · Two types of carnitine deficiency states exist. Primary carnitine deficiency is a genetic disorder of the cellular carnitine-transporter system that usually manifests itself by five years of age with symptoms of cardiomyopathy, skeletal-muscle weakness, and hypoglycemia.